The USB version of SAFER is provided to institutions for use by multiple users at their facility in accordance with the SAFER Institutional Site License Agreement. SAFER is a 37-minute narrated video presentation, post-test, answer key, and PowerPoint presentation providing an introduction to the science of sleep and information on the effects of sleep deprivation, specifically in regards to medical students, who face unique demands and work-related stresses. SAFER provides concrete, implementable suggestions for management of fatigue and sleepiness during residency. Management of fatigue is enhanced when there is an understanding of the influences of circadian and homeostatic processes. SAFER helps residents apply knowledge of these processes in deciding when and how long to sleep, and what fatigue countermeasures can be used.